Intermediates of sunitinib

Intermediates of sunitinib - Names and Identifiers

Name	(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine
Synonyms	Afatinib-1 Intermediates of sunitinib Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine 7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenyl)amino-6-aminoquinazoline (S)-N4-(3-Chloro-4-Fluorophenyl)-7-(Tetrahydrofuran-3-Yloxy) Quinazoline-4,6-Diamine (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diammine N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-[[(S)-tetrahydro-3-furanyl]oxy]quinazoline 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]- 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-amine-7-[[(3S)-tetrahydro-3-furanyl]oxy]-
CAS	314771-76-1
EINECS	1312995-182-4

Intermediates of sunitinib - Physico-chemical Properties

Molecular Formula	C18H16ClFN4O2
Molar Mass	374.8
Density	1.473±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	559.0±50.0 °C(Predicted)
pKa	5.89±0.30(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Sensitive	Irritant
MDL	MFCD18642925
Use	This product is for scientific research only and shall not be used for other purposes.

Intermediates of sunitinib - Reference Information

introduction

N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furyl] oxygen]-4, 6-quinazoline diamine is a light yellow solid, which can be used as a pharmaceutical intermediate for pharmaceutical synthesis and experimental research.

use

quinazoline ring is a dominant skeleton structure that can combine with a variety of biological macromolecules to produce different biological activities. In particular, N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furyl] oxy]-4, 6-quinazoline diamine is particularly prominent as an intermediate in the synthesis of antitumor drugs. It is expected that in the near future, through the overall design and optimization of the quinazoline ring in this molecule to develop high-efficiency and low-toxicity anticancer drugs, there will be breakthrough progress, which will contribute to human life and health.

Last Update：2024-04-09 02:00:01

Shanghai Macklin Biochemical Co., Ltd

Featured ProductsSpot supply

Product Name: N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine Visit Supplier Webpage Request for quotation
CAS: 314771-76-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328

WhatsApp: +86-18821248368

CHEMBSF (Shanghai) Biomedical Technology Co., Ltd

Spot supply

Product Name: (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine Request for quotation
CAS: 314771-76-1
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379

Jiangsu Pules Biotechnology Co.,Ltd.

Product Name: (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine Request for quotation
CAS: 314771-76-1
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830

Hubei Rhema Reference Materials Technology Co., Ltd.

Spot supply

Product Name: (S)-N4-(3-chloro-4-fluorophenyl)-7-((tetrahydrofuran- 3-yl) oxy)quinazoline-4,6-diamine Request for quotation
CAS: 314771-76-1
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249

Wechat: 15787876101

Nantong Reform Petro-Chemical CO., LTD.

Spot supply

Product Name: (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine Request for quotation
CAS: 314771-76-1
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865

Send QQ message
Wechat: chemical6666

Shanghai Amole Biotechnology Co., Ltd.

Spot supply

Product Name: (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine Request for quotation
CAS: 314771-76-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365

Wechat: 18916960931

SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.

Spot supply

Product Name: (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine Visit Supplier Webpage Request for quotation
CAS: 314771-76-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922

Wechat: 18621343501
WhatsApp: +86-18621343501

BOC Sciences

Spot supply

Product Name: Afatinib Impurity B Visit Supplier Webpage Request for quotation
CAS: 314771-76-1
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog